Excited to hit the road and soak up some culture in 2022?  Several museums, theaters, concert venues, and cultural experiences are set to reopen in major North American cities in the coming year, including locations in New York City, Los Angeles, Key West, Fla., and more. A handful of popular tourist destinations are also planning milestone anniversary celebrations in 2022 — giving you plenty of new reasons to revisit some of your favorite places.

Here are just seven North American destinations you may want to keep your eye on for 2022 vacations.

Explore the Ahmanson Theatre, Underground Museum & More in Los Angeles

This culture-filled city — which is experiencing its largest downtown development boom in nearly a century — will celebrate the reopening of the Underground Museum after a 20-month closure. The artistic hub operates out of four converted storefronts in the Arlington Heights neighborhood and brings major artistic opportunities — plus yoga and meditation classes — to visitors for free. The footlights will again shine at the Ahmanson Theatre, with performances beginning Jan. 16, 2022. And the Academy Museum of Motion Pictures, the largest devoted to exploring the art and science of movies and moviemaking, just recently reopened. Its limited Hayao Miyazaki exhibit will run through June 5, 2022. 

Also making its debut in spring 2022 is the Conrad Los Angeles, which is part of Related Companies’ mixed-use development, The Grand LA, in downtown Los Angeles and offers convenient access to some of the most prominent cultural venues in the city. Designed by Architect Frank Gehry, the hotel will offer rooms with a bold and contemporary design featuring floor-to-ceiling windows; locally-inspired culinary experiences; a rejuvenating spa, private pool deck and much more. The 28-story hotel will also offer views of one of Gehry’s other architectural wonders, the Walt Disney Concert Hall.

Explore the New Museum of Broadway in New York City

The highly anticipated Museum of Broadway will make its grand debut in summer 2022, offering visitors the chance to walk through a timeline of Broadway milestone moments, beloved shows — and even learn about the making of a Broadway show. Tickets are also already on sale for the immersive Netflix Stranger Things: The Experience, which will debut in May 2022. It will offer a Hawkins Lab Immersive Experience (where strange things are happening once again), a Mix-Tape Area for fun photo ops, and themed food and beverage.

While in town, check out the 1,878-room New York Hilton Midtown, which reopened in October, or Conrad New York Downtown, where families can add on the Little Kid Big City adventure kit, or a self-guided kid-friendly NYC tour with a prize upon completion.

Listen to Live Music in Las Vegas

According to a recent study by Hilton, nearly a quarter of Americans ranked Las Vegas as their top post-pandemic destination — and 2022 will be a great time for music lovers to visit, as a lineup of new top-tier artists have already announced residencies for the coming year.

Over the last three years, Hilton has nearly doubled its footprint in Las Vegas, including the recent opening of Resorts World Las Vegas, which includes Las Vegas Hilton at Resorts World and Conrad Las Vegas at Resorts World, bringing over 40 food and beverage options, luxurious accommodations, concert and entertainment venue, and access to all the fun that the city has to offer.

This year, Hilton also debuted Virgin Hotels Las Vegas, Curio Collection by Hilton as part of its Las Vegas portfolio. The resort boasts more than 1,500 chambers and suites, 15 distinct and unique F&B outlets, including the signature Shag Room, Kassi Beach House from restaurateur Nick Maters, Night + Market from award-winning Chef Kris Yenbamroong, Todd English’s Olives, multiple entertainment venues, Mohegan Sun Casino and more, as part of its Las Vegas portfolio. The resort boasts more than 1,500 chambers and suites, 15 distinct and unique F&B outlets, including the signature Shag Room, Kassi Beach House from restaurateur Nick Maters, Todd English’s Olives, multiple entertainment venues, and the Mohegan Sun Casino, to name a few.

Additionally, Hilton’s first luxury property in the destination and a non-gaming hotel, Waldorf Astoria Las Vegas, will also debut a floor-to-ceiling renovation of all 392 spacious guestrooms and suites featuring a new sophisticated, refined, and feminine design aesthetic that reflects the colors and feel of the surrounding desert landscape.

Celebrate a Theme Park Milestone in Orlando

Walt Disney World® just began celebrating its 50th anniversary with an 18-month-long string of golden anniversary festivities that includes new theme park attractions and nighttime spectaculars. 

Signia by Hilton Orlando Bonnet Creek recently marked the first opening for the brand. Nestled in a 482-acre nature preserve, both the new Signia by Hilton Orlando Bonnet Creek and Waldorf Astoria Orlando offer business and leisure travelers access to a sprawling complex of amenities, from a lagoon-style pool and a three-acre lazy river to a world-class spa, and an 18-hole championship golf course. In addition to the nature preserve, both properties are surrounded by Walt Disney World® parks and many of the rooms offer breathtaking views of them. As Official Walt Disney World® Hotels, complimentary transportation to the Disney theme parks and Disney Springs® allows for an easy lift, and early theme park entry gives guests more fun with 30-minute early entry to any Walt Disney World® theme park every day! 

For a magical getaway, Hilton Orlando Lake Buena Vista and Hilton Orlando Buena Vista Palace are resorts just steps from Disney Springs®, directly accessible by a Pedestrian Skybridge. Experience personalized service throughout the resort, refreshing amenities, and create memorable experiences you’ll never forget. Enjoy a sprinkle of Disney magic with select rooms featuring incredible views of Disney Springs® and evening fireworks from Epcot. As Official Walt Disney World® Hotels, guests enjoy early entry and complimentary transportation to Disney Theme Parks.

Drink in the Sunshine at Key West’s 200th Anniversary Celebration

The city of Key West, Fla., will celebrate its 200th anniversary of settlement with a year-long celebration that will include an art exhibit at the Key West Museum of Art & History, monthly destination-themed movie screenings, parades, walking tours, and more. In late 2022, the Tortugas Harbor Lighthouse at Dry Tortugas National Park will reopen after its first full renovation since its construction in 1876.

The Conch Republic's most historic and luxurious property, Casa Marina Key West, A Waldorf Astoria Resort, is culminating its 100th anniversary this year and guests staying at the resort next year, can take part in bicentennial programming to celebrate Key West’s 200th anniversary. Guests can also book a stay to celebrate Key West’s bicentennial at The Reach Key West, Curio Collection by Hilton. Visitors can bask in the sun and lounge in the pool at this beachfront property, enjoy sailing, snorkeling and scuba diving or discover the best sites of Key West including The Ernest Hemingway Home and Museum.

Join Old San Juan’s 500th Anniversary Festivities in Puerto Rico

Old San Juan — the oldest city in the United States — will celebrate its 500th anniversary in 2022 with a series of art exhibits, parades, academic forums, and concerts.

Tap further into the destination’s rich history and enjoy a short stroll along the cobblestone streets of Old San Juan while staying at Caribe Hilton. Guests can also enjoy the hotel’s three oceanfront pools, water sports, spa, and the hotel’s signature piña colada. For travelers wishing to stay closer to Isla Verde Beach while still participating in anniversary activities, Embassy Suites by Hilton San Juan Hotel & Casino offers spacious two-room suites, an outdoor lagoon-style pool, a reserved beach area with chairs and umbrellas, and San Juan’s friendliest on-site Oasis casino.

Soak in the Sun in Cancun, Mexico

Business is booming in Mexico, where in September of 2021, arrivals to Cancun Airport were greater than pre-pandemic numbers, according to ASUR data. Next year is the perfect time to find out why the Yucatán Peninsula is a favored destination for a much-needed respite and refreshed setting, whether it’s a solo trip, spa-cation, honeymoon, or girlfriend getaway.

Following the opening of Hilton Vallarta Riviera All-Inclusive Resort and Hilton Cancun, an All-Inclusive Resort, Hilton plans to welcome even more hotels to its portfolio of more than 80 hotels open and welcoming travelers across Mexico. More than 30 hotels form part of Hilton’s development pipeline, including Conrad Tulum Riviera Maya, now accepting reservations beginning Jan. 15, 2022, which will be a haven on the secluded eastern coast of the Yucatán Peninsula with seven restaurants and bars. Hilton Tulum All-Inclusive Resort is expected to open in spring 2022 and will introduce travelers to a premier all-inclusive experience with unrestricted ocean views. And Waldorf Astoria Cancun, expected to open in fall 2022, and will be set on 100 acres of secluded coastline in the Riviera Maya combining rich Mexican heritage with refined sophistication.